Summary of the genetic disorder and symptoms
Progeria or Hutchinson-Gilford Progeria syndrome (HGPS) is a rare and fatal condition that accelerates age appearance in children (PRF). The name, coming from the greek word meaning ¨prematurely old¨,is caused by a mutation in the LMNA (lamin-a) gene (PRF). LMNA produces lamin which is a protein that holds the nucleus of a cell together. The defective Lamin A protein is believed to cause the nucleus to be unstable and cellular instability, Leading to the process of premature ageing according to the https://www.progeriaresearch.org/ website. Symptoms of Progeria appear 2 years after birth, Symptoms like growth failure, loss of body fat and hair, aged-looking skin, stiffness of joints, hip dislocation, generalized atherosclerosis, cardiovascular (heart) disease and stroke.